Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy


Paper Science Biology
doi.org/10.1038/s41556-024-01572-y

We constructed a model which could qualitatively display how high/low affinities between autophagy receptors lead to phase separation on the surface of the cargo, thus ultimately inducing selective autophagy.

iGEM 2023 – Grand Jamboree


Science Biology

Over the past months I was supervising and helping the current iGEM Team from Freiburg in their Journey towards the Grand Jamboree. This weekend, we finally had the opportunity to present our work – CELLECT.

iGEM 2023


Science Biology

I am excited to share that I will be participating in this years iGEM competition as a supervisor. I will advise the students’ who are modeling their experimental setup. We aim to establish a concise model and acquire relevant parameters in a timely manner. This will probably be a more demanding task than initially believed That being said, the iGEM Freiburg Team is very motivated and I hope to be sharing more details in the coming months.

Physics of Life Conference


Science Biology Math Physics

I was at the physics of life conference this week